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GATA1 — STAT3
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Ezoe et al., J Biol Chem 2005
:
In addition, endogenous GATA-1 was found to interact with STAT3 in normal megakaryocytes, suggesting that
GATA-1 may
inhibit STAT3 activity in normal hematopoietic cells ... Furthermore, we found that
GATA-1 suppressed
STAT3 activity through its N-zinc finger domain
Huang et al., J Clin Invest 2007
(Inflammation...) :
Enforced expression of STAT1, IRF-1, or
GATA-1 enhanced phosphorylation of STAT1,
STAT3 , and STAT5 in cultured Gata1-deficient murine megakaryocytes, with concomitant megakaryocyte maturation
Yao et al., Exp Hematol 2009
:
Recently,
GATA-1 , a key transcription factor involved in hematopoietic cell development, was shown to directly
inhibit STAT3 activity in vivo ... Recently,
GATA-1 , a key transcription factor involved in hematopoietic cell development, was shown to directly
inhibit STAT3 activity in vivo