Gene interactions and pathways from curated databases and text-mining

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GATA1 — STAT3

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Ezoe et al., J Biol Chem 2005 : In addition, endogenous GATA-1 was found to interact with STAT3 in normal megakaryocytes, suggesting that GATA-1 may inhibit STAT3 activity in normal hematopoietic cells ... Furthermore, we found that GATA-1 suppressed STAT3 activity through its N-zinc finger domain
Huang et al., J Clin Invest 2007 (Inflammation...) : Enforced expression of STAT1, IRF-1, or GATA-1 enhanced phosphorylation of STAT1, STAT3 , and STAT5 in cultured Gata1-deficient murine megakaryocytes, with concomitant megakaryocyte maturation
Yao et al., Exp Hematol 2009 : Recently, GATA-1 , a key transcription factor involved in hematopoietic cell development, was shown to directly inhibit STAT3 activity in vivo ... Recently, GATA-1 , a key transcription factor involved in hematopoietic cell development, was shown to directly inhibit STAT3 activity in vivo