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AKT1 — FUT7
Text-mined interactions from Literome
Qi et al., Eur J Biochem 2003
(Carcinoma, Hepatocellular...) :
The upregulation of cell surface SLe ( x ) and alpha-1,3-fucosyltransferase-VII ( alpha-1,3 Fuc T-VII, enzyme for SLe ( x ) synthesis ) was also mediated by PI3K and PKB, since LY294002 and
AS-PKB also
reduced the expressions of SLe ( x ) and alpha-1,3
FucT-VII , and attenuated the response to insulin
Yang et al., Cell death & disease 2013
:
Moreover,
FUT4 induced activation of phosphatidylinositol 3-kinase
(PI3K)/Akt , and inactivation of GSK3ß and nuclear translocation of NF-?B, resulting in increased Snail and MMP-9 expression and greater cell motility