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Wang et al., Clin Cancer Res 2009
(Endometrial Neoplasms) :
Progesterone induction of DKK1 and FOXO1 results in inhibition of Wnt signaling in the human endometrium
Manolopoulos et al., Mol Psychiatry 2010
(Alzheimer Disease...) :
Wnt inhibition may also result in a sustained activation of FoxO proteins with induction of apoptosis and neuronal loss, thereby completing a vicious circle from oxidative stress, InsRes and hyperglycaemia back to the formation of ROS and consecutive neurodegeneration
Dieudonné et al., J Bone Miner Res 2012
(Bone Neoplasms...) :
Doxorubicin modulated Foxo3a binding on syndecan-2 gene promoter and induced Foxo dependent inhibition of Wnt/TCF activity