Gene interactions and pathways from curated databases and text-mining

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FLT3 — MAPK14

Text-mined interactions from Literome

Spiekermann et al., Clin Cancer Res 2003 (Cell Transformation, Neoplastic...) : FLT3-ITD mutants induce an autophosphorylation of the receptor, interleukin 3-independent growth in Ba/F3 cells, and a strong STAT5 and mitogen activated protein kinase ( MAPK ) activation ... The ligand stimulated FLT3-WT receptor activated AKT and MAPK , but not STAT5
Desterke et al., Cancer Res 2011 (MAP Kinase Signaling System...) : FLT3 mediated p38-MAPK activation participates in the control of megakaryopoiesis in primary myelofibrosis