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FGFR4 — MAPK3
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Hart et al., Oncogene 2000
(Cell Transformation, Neoplastic) :
Phosphorylation of Shp2, PLC-gamma, and
MAPK was also
stimulated by all three ` TDII-like '
FGFR derivatives
Koziczak et al., Oncogene 2004
(Breast Neoplasms) :
The repression of
FGFR activity
caused downregulation of
MAPK in MDA-MB-415 and MDA-MB-453 cells
Easton et al., J Neurochem 2006
(Neuroblastoma) :
In addition to Shc,
fibroblast growth factor receptor substrate 2 (FRS2) is
required for the BDNF induced activation of
MAPK
Kuslak et al., Differentiation 2007
(MAP Kinase Signaling System) :
Blocking FGFR activation with PD173074 showed that activation of
extracellular signal regulated kinase 1/2 ( ERK1/2 ) in the UGS is
dependent on
FGFR signaling
Mavila et al., PloS one 2012
(Liver Neoplasms) :
FGF Receptor ( R ) activation
resulted in the downstream activation of
MAPK , PI3K-AKT, and ß-catenin pathways, as well as cellular proliferation