Gene interactions and pathways from curated databases and text-mining

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FGF4 — WNT11

Text-mined interactions from Literome

Wilson et al., Nature 2001 : Continual Wnt signalling blocks the response of epiblast cells to FGF signals, permitting the expression and signalling of BMP to direct an epidermal fate
Treichel et al., Genes Dev 2003 : We present evidence that mBtd is required during early limb development to maintain, but not to initiate Wnt/beta-catenin dependent FGF , Shh, and BMP mediated signaling
Wu et al., Dev Biol 2005 : In addition, Wnt signaling induces neural crest when its posteriorizing activity is blocked by inhibition of FGF signaling in neuralized explants
Katoh et al., Int J Mol Med 2006 : WNT signaling activation in progenitor cells leads to the growth regulation of progenitor cells themselves through SPRY4 induction, and also to the growth stimulation of proliferating cells through FGF secretion
Olivera-Martinez et al., Development 2007 : FGF promotes Wnt8c expression, which persists in the neuroepithelium as FGF signalling declines
Katoh et al., Cancer Biol Ther 2007 (Helicobacter Infections...) : WNT-beta-catenin-TCF/LEF signaling induces upregulation of MYC, CCND1, WISP1, FGF20 , JAG1 and DKK1 genes
Falk et al., Cell stem cell 2008 : Consistent with this phenotype, self-renewal of mutant neuroepithelial stem cells is enhanced in the presence of FGF and requires Wnt signaling
Ambrosetti et al., Mol Cell Biol 2008 : To analyze the effect of FGF on Wnt signaling in osteoblasts, we created reporter cell lines where a Wnt-responsive promoter drives luciferase expression and showed that Wnt3a induced luciferase expression was specifically inhibited by FGF treatment
Yin et al., Dev Biol 2008 : Here we have identified a robust regulatory network in which mesenchymal FGF signaling regulates beta-Catenin mediated WNT signaling in lung mesenchyme
Huang et al., Development 2009 : FGF signaling also promoted the expression of the Wnt antagonist Sfrp1 and suppressed Wnt signaling in the prospective eyelid epithelial cells, independently of BMP function
Quarto et al., J Bone Miner Res 2010 : Moreover, fibroblast growth factor 2 (FGF-2) treatment induces phosphorylation of GSK-3beta and increases the nuclear levels of beta-catenin in osteoblasts, suggesting that enhanced activation of Wnt signaling might be mediated by FGF
Aman et al., Dev Biol 2011 : We have previously shown that Wnt/ß-catenin signaling induces Fgf signaling and that interactions between these two pathways regulate primordium migration and prosensory organ formation
Paek et al., Dev Dyn 2012 : These results, together with previous ones demonstrating that increased WNT signaling in the anterior neural plate increases FGF expression, suggest that the levels of WNT and FGF signaling regulate telencephalic versus mid-hindbrain fates
van der Velden et al., Development 2012 : Exogenous application of FGF4, as well as enhanced stimulation of Fgf signaling by overactivated Wnt signaling in apc mutants, partially restores the fin developmental program ... Exogenous application of FGF4 , as well as enhanced stimulation of Fgf signaling by overactivated Wnt signaling in apc mutants, partially restores the fin developmental program
Matsuda et al., Development 2013 (Wnt Signaling Pathway) : FGF receptor signaling, in turn, inhibits Wnt signaling
Minor et al., Development 2013 : FGF signaling regulates Wnt ligand expression to control vulval cell lineage polarity in C. elegans