Gene interactions and pathways from curated databases and text-mining

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FGF3 — IGF1

Text-mined interactions from Literome

Cao et al., Zhonghua Yan Ke Za Zhi 1997 : ( 1 ) EGF, b-FGF , IGF-I significantly increased the DNA 6.6-12.2 times in human RPE cells in comparison with the control, the rank order of potency of the factors being EGF > b-FGF > IGF-I
Rosenthal et al., Mol Endocrinol 1991 : Concomitantly, FGF resulted in a 60-70 % increase in IGF-I binding compared to that in control myoblasts ... Scatchard analyses and studies of gene expression demonstrated that the increased IGF-I binding induced by FGF reflected parallel increases in IGF-I receptor content and mRNA abundance
Kalluri et al., Eur J Neurosci 2007 : However, FGF-2 ( ERK activator ) in the presence of IGF-I ( Akt activator ) increased the proliferation of cells
Jeschke et al., Gene Ther 2007 : IGF-I , KGF and their combination cDNA treatment significantly ( P < 0.05 ) accelerated re-epithelization, increased IGF-I, KGF, FGF , VEGF and collagen type IV expression, while it had no effect on collagen type I and III expression
Fazeli et al., J Clin Endocrinol Metab 2010 : In a transgenic mouse model, FGF-21 reduces IGF-I levels by inhibiting signal transducer and activator of transcription-5, a mediator of the intracellular effects of GH
Naville et al., Mol Cell Endocrinol 1990 : Human chorionic gonadotropin ( hCG ) and basic fibroblast growth factor (FGF) stimulate in a dose dependent manner IGF-I production by Leydig cells ... The secretion of IGF-I by Sertoli cells was stimulated by FSH and FGF
Kralisch et al., J Endocrinol 2013 (Insulin Resistance) : Notably, FGF21 significantly inhibited IGF1 secretion into HepG2 cell culture supernatants in preliminary in vitro experiments
Penhoat et al., J Biol Chem 1989 : The basal secretion of IGF-I ( 6 +/- 1 ng/48 h/10 ( 6 ) cells ) was stimulated 3-, 4.5-, and 9.5-fold by fibroblast growth factor , angiotensin II ( A-II ), and ACTH, respectively, but not by growth hormone
Wilkie et al., Growth Regul 1995 : This study describes the effect of acidic and basic fibroblast growth factor (FGF) on DNA synthesis in chick satellite cells in vitro and interactions with insulin-like growth factor-I (IGF-I) and exogenous heparin
Ververis et al., Circ Res 1993 : PDGF and FGF but not Ang II regulate vascular IGF I receptors through a PKC dependent pathway
Scheinowitz et al., Int J Cardiol 1997 (Disease Models, Animal...) : IGF has been found to promote physiological forms of cardiac hypertrophy, and FGF induces neovascularization