UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

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CHUK — FASLG

Pathways - manually collected, often from reviews:

NCI Pathway Database FAS (CD95) signaling pathway: FASLG/FAS (trimer)/FADD/FADD/RIP complex (FAS-FASLG-FADD-RIPK1) → IKK complex complex (CHUK-IKBKB-IKBKG) (modification, activates)
Kreuz et al., J Cell Biol 2004
Evidence: mutant phenotype, assay
NCI Pathway Database FAS (CD95) signaling pathway: FASLG/FAS (trimer)/FADD/FADD/CASP8/CASP8 complex (FAS-FASLG-FADD-CASP8) → IKK complex complex (CHUK-IKBKB-IKBKG) (modification, activates)
Kreuz et al., J Cell Biol 2004
Evidence: mutant phenotype, assay