Gene interactions and pathways from curated databases and text-mining

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CASP7 — FAM168B

Text-mined interactions from Literome

Breckenridge et al., J Cell Biol 2003 : p20 strongly sensitized mitochondria to caspase-8 induced cyt.c release, whereas prolonged expression of p20 on its own ultimately induced caspase activation and apoptosis through the mitochondrial apoptosome stress pathway
Nagy et al., Pathol Oncol Res 2006 (Colonic Neoplasms) : TRAIL alone induced only partial activation of caspase-3 ( p20 ), while the combination of TRAIL and proteasome inhibition led to the full proteolytic activation of caspase-3 ( p17 )