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F2R — TLR4

Text-mined interactions from Literome

Moretti et al., Mucosal Immunol 2008 (Aspergillosis...) : This occurred by TLR regulation of PAR signaling, with TLR2 promoting PAR(1) activity, and TLR4 suppressing PAR(2) activity
Chung et al., Immunol Lett 2010 (Bacteroidaceae Infections...) : PAR1 or PAR2 knock-down resulted in up-regulated NOD1 and NOD2 expression with P. gingivalis or F. nucleatum stimulation ( p < 0.01 ), as well as enhanced TLR2 and TLR4 expression when cells were stimulated by bacteria that utilize TLR2 or TLR4, respectively