Gene interactions and pathways from curated databases and text-mining

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ETS1 — PARP14

Text-mined interactions from Literome

Soldatenkov et al., Oncogene 1999 (Sarcoma, Ewing) : The participation of ETS in the regulation of PARP gene expression was further demonstrated in EWS cells stably transfected with Ets1 antisense cDNA constructs ... Antisense mediated down-regulation of endogenous ETS1 resulted in the inhibition of PARP expression in EWS cells, and sensitized these cells to ionizing radiation ... These data provide support for ETS regulation of PARP expression levels, and implicate ETS transcription factors in the radiation response of EWS cells
Soldatenkov et al., Oncogene 2002 (Sarcoma, Ewing) : Previously, we cloned the PARP gene promoter region from EWS cells, showed that it contained multiple ETS binding sites and demonstrated a positive regulation of PARP by ETS1