Gene interactions and pathways from curated databases and text-mining

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ESAT — MAPK3

Text-mined interactions from Literome

Peng et al., J Biol Chem 2011 (Latent Tuberculosis) : Incubation of peripheral blood mononuclear cells with ESAT-6 induced activation of p38 MAPK, and inhibition of p38 MAPK with SB203580 reversed ESAT-6 inhibition of M. tuberculosis stimulated IFN-? production by peripheral blood mononuclear cells from subjects with latent tuberculosis infection
Boggaram et al., J Biol Chem 2013 (MAP Kinase Signaling System...) : ESAT-6 activated ERK and p38 MAPK phosphorylation and rapidly induced reactive oxygen species ( ROS ) production