Gene interactions and pathways from curated databases and text-mining

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EPO — IGF1

Text-mined interactions from Literome

Mioni et al., Acta Endocrinol (Copenh) 1992 : GnRH, hCG, IGF-I and EGF did not induce any modification of recombinant human erythropoietin-specific binding
Sohmiya et al., J Endocrinol 2005 : Human growth hormone and insulin-like growth factor-I inhibit erythropoietin secretion from the kidneys of adult rats ... Growth hormone (GH) and insulin-like growth factor-I (IGF-I) play important roles in erythropoiesis and erythro-poietin (EPO) secretion ... We examined the effects of GH and IGF-I on EPO production in adult rat kidney and liver in vivo and in vitro
Kim et al., Neuroreport 2008 (Astrocytoma) : Interestingly, blocking the potential action of secreted EPO on LN215 cells with EPO antibody, EPO receptor antibody, and soluble EPO receptor significantly suppressed the effect of IGF-1 on the biosynthesis of EPO