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EPHA4 — IGF1
Text-mined interactions from Literome
Smith et al., Exp Cell Res 2004
(Lymphoma, T-Cell...) :
Interestingly,
EphA3 expression in CD28 stimulated Jurkat cells was
enhanced by
IGF-1 or by overexpression of the IGF-1R, and was suppressed by anti-IGF-1R blocking antibodies
Jing et al., Cell reports 2012
:
EphA4 forms a complex with the GH receptor, JAK2, and STAT5B and
enhances Igf1 expression predominantly via the JAK2 dependent pathway, with some direct effect on STAT5B