Gene interactions and pathways from curated databases and text-mining

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AKT1 — EPHA3

Text-mined interactions from Literome

Yang et al., Cell Signal 2011 : Indeed, EphA2 can inhibit Akt phosphorylation induced by oncogenic mutations of not only PTEN but also PI3 kinase
Guo et al., PloS one 2011 (Neoplasm Invasiveness...) : We found that down-regulation of ETK in bladder cancer cells attenuated STAT3 and AKT activity whereas exogenous overexpression of ETK had opposite effects, suggesting that deregulation of ETK may attribute to the elevated activity of STAT3 and AKT frequently detected in bladder cancer