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ELN — IGF1
Text-mined interactions from Literome
Bunda et al., Am J Pathol 2007
:
Aldosterone
induces elastin production in cardiac fibroblasts through activation of
insulin-like growth factor-I receptors in a mineralocorticoid receptor independent manner
Burkhardt et al., Placenta 2009
(Fetal Growth Retardation...) :
Serum levels of
IGF-I , a
regulator of
elastin synthesis, were significantly lower in IUGR cord blood ( P < 0.01 ) than in AGA cord blood
Noguchi et al., Pediatr Res 1991
:
IGF-I stimulates
tropoelastin synthesis in neonatal rat pulmonary fibroblasts ... We have examined the
effect of
IGF-I on
tropoelastin (TE) synthesis in cultured rat neonatal pulmonary fibroblasts, because this growth factor has been shown to stimulate TE synthesis in vascular smooth muscle cells
Sesso et al., Am J Hypertens 2010
(Birth Weight...) :
Small-for-gestational-age children exhibited elevated amounts of MMP-2, MMP-9, MMP-2/TIMP-2 ratio, MMP-9/TIMP-2 ratio, as well as lower concentration of
IGF-I ( P < 0.01 ), a known
regulator of
elastin synthesis
Badesch et al., Biochem Biophys Res Commun 1989
:
Insulin-like growth factor I stimulates
elastin synthesis by bovine pulmonary arterial smooth muscle cells ...
Insulin-like growth factor I stimulates mitogenesis in smooth muscle cells, and
upregulates elastin synthesis in embryonic aortic tissue ... Therefore, we studied the
effect of
IGF-I on
elastin and total protein synthesis by pulmonary arterial smooth muscle cells in vitro
Foster et al., Coll Relat Res 1987
:
Insulin-like growth factor I , somatomedin C,
induces the synthesis of
tropoelastin in aortic tissue
Jensen et al., J Biol Chem 1995
:
Transcriptional
regulation of the
elastin gene by
insulin-like growth factor-I involves disruption of Sp1 binding
Wolfe et al., J Biol Chem 1993
:
Insulin-like growth factor-I regulates transcription of the
elastin gene