Gene interactions and pathways from curated databases and text-mining

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CASP5 — ELAVL1

Text-mined interactions from Literome

Beauchamp et al., Cell Death Differ 2010 : Disruption of caspase activity in cultured myoblasts or knocking out the caspase-3 gene in mice significantly reduced HuR cleavage and the cytoplasmic accumulation of HuR in muscle fibers
Dickson et al., J Biol Chem 2012 (Alphavirus Infections) : Sindbis virus induced HuR relocalization was mechanistically distinct from the movement of HuR observed during a cellular stress response, as there was no accumulation of caspase mediated HuR cleavage products
von Roretz et al., Cell Death Differ 2013 : In the absence of an apoptotic stimuli, HuR associates with and promotes the expression of caspase-9 and prothymosin a ( ProT ) mRNAs, and pro- and antiapoptotic factors, respectively, both of which have been characterized as important players in determining cell fate