Gene interactions and pathways from curated databases and text-mining

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ARF6 — EHMT1

Text-mined interactions from Literome

Paliwal et al., Mol Cell Biol 2006 (Colonic Neoplasms) : Interaction with ARF resulted in proteasome dependent CtBP degradation ... Both ARF induced CtBP degradation and CtBP small interfering RNA led to p53 independent apoptosis in colon cancer cells ... ARF induction of apoptosis was dependent on its ability to interact with CtBP , and reversal of ARF induced CtBP depletion by CtBP overexpression abrogated ARF induced apoptosis
Chen et al., EMBO J 2010 : The p53 activator ARF inhibits SUV39H1 and EHMT1 binding to MDM2 and reduces MDM2 associated methyltransferase activity