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AKT1 — EHMT1
Text-mined interactions from Literome
González et al., Regul Pept 2005
:
In conclusion,
GLP-1 , like insulin, stimulates glucose uptake, and this
involves activation of
PI3K/PKB , p44/42 MAPKs, partially p70s6k, and possibly PKC ; Ex-4 and Ex-9 both have GLP-1-like effect upon glucose transport, in which both share with GLP-1 an activation of PI3K/PKB -- partially in the case of Ex-4 -- and p44/42 MAPKs but not p70s6k
Sancho et al., J Mol Endocrinol 2005
(Diabetes Mellitus, Experimental) :
In cells from STZ-rats the magnitude of the above parameters was, in general, comparable to that in normal animals, with some exceptions : basal PI3K activity and lipogenesis were higher,
GLP-1 , Ex-4 and Ex-9 failed to modify basal lipogenesis but
increased PKB activity, insulin failed to affect the activity of MAPKs and the insulin induced glucose uptake was impaired