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EGFR — HIF1A

Text-mined interactions from Literome

Li et al., Int J Mol Med 2006 : EGFR kinase inhibitor, PD153035, inhibited UV-induced HIF-1alpha and VEGF protein expression in a dose dependent manner
Lee et al., Carcinogenesis 2009 (Anoxia) : Methyl-beta cyclodextrin ( MbetaCD ), which induces cholesterol depletion, upregulated HIF-1alpha even under normoxic conditions and this upregulation required epidermal growth factor receptor (EGFR) and extracellular signal regulated kinase 1 and 2 activation, but not Akt activation