Gene interactions and pathways from curated databases and text-mining

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ECM1 — IGF1

Text-mined interactions from Literome

Oosterlaken-Dijksterhuis et al., Breast Cancer Res Treat 1999 (Mammary Neoplasms, Animal) : The difference between IGF-I and RA was an enhanced IGFBP-5 binding to the extracellular matrix ( ECM ) by RA, whereas IGF-I reduced binding to the ECM
Lawrance et al., Inflamm Bowel Dis 2001 (Inflammation...) : Our aim was to determine whether TGF-beta1 and IGF-1 are involved in intestinal ECM collagen regulation and what impact the inflammatory infiltrate has on their expression
Gooch et al., J Biol Chem 2001 (Hypertrophy) : IGF-I induced hypertrophy as determined by an increase in cell size and an increase in protein to DNA ratio and increased accumulation of extracellular matrix ( ECM ) proteins ... Inhibition of either MAPK or PI3K, however, had no effect on IGF-I induced hypertrophy or ECM production ... Therefore, IGF-I induces hypertrophy and increases ECM accumulation in MCs ... Therefore, IGF-I induces hypertrophy and increases ECM accumulation in MCs
Daian et al., J Invest Dermatol 2003 (Keloid) : Insulin-like growth factor-I enhances transforming growth factor-beta induced extracellular matrix protein production through the P38/activating transcription factor-2 signaling pathway in keloid fibroblasts
Singh et al., International journal of biological sciences 2007 : Recently we demonstrated that IGF-1 expression is increased in the diabetic kidney and that it may involve in renal hypertrophy and extracellular matrix protein ( ECM ) accumulation in mesangial cells as seen in diabetic glomerulopathy
Etheredge et al., Invest Ophthalmol Vis Sci 2009 : The effects of IGF-I , TGF-beta1, FGF-2, and PDGF on proliferation and ECM production by primary cultured bovine keratocytes were evaluated
Liu et al., Chin Med J (Engl) 2010 (Liver Cirrhosis) : Insulin-like growth factor binding protein related protein 1 ( IGFBPrP1 ) can activate hepatic stellate cells and increase extracellular matrix ( ECM ) in vitro
Devi et al., Biochim Biophys Acta 2011 (Diabetic Retinopathy) : GSK-3ß/CREB axis mediates IGF-1 induced ECM/adhesion molecule expression, cell cycle progression and monolayer permeability in retinal capillary endothelial cells : Implications for diabetic retinopathy ... We therefore examined the effect of insulin-like growth factor (IGF)-1 on ECM/adhesion molecule expression, cell cycle regulation and monolayer permeability in an endothelial cell line ( TR-iBRB2 )
Corrêa-Giannella et al., Diabetology & metabolic syndrome 2012 : The objective of the present study was to investigate the effect of an AGE modified extracellular matrix protein on IGF-I induced SMC proliferation and on the IGF-I-IGF binding protein 4 (IGFBP-4) axis under basal conditions and after stimulation with PDGF-BB
Pricci et al., Endocrinology 1996 : These experiments in cultured human mesangial cells were aimed at assessing the effects of IGF-I and IGF-II, compared with those of TGFbeta, on 1 ) ECM medium accumulation and gene expression, and 2 ) total protein synthesis and cell proliferation