Gene interactions and pathways from curated databases and text-mining

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DYNLL1 — NOS1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Roczniak et al., American journal of physiology. Renal physiology 2000 : In summary, our data show that PIN , a specific inhibitor of nNOS activity, is expressed in the IMCD, a site of high nNOS expression in the kidney
Chang et al., Mol Cell Biol 2000 : This increased nNOS activity as well as increased nNOS dimer after NGF withdrawal were inhibited by COX-2 or DLC/PIN overexpression
Yu et al., Brain Res Mol Brain Res 2002 (Synaptic Transmission) : Our data indicate that the protein inhibitor of nNOS (PIN) binds to protein kinase A inhibitors ( PKIs ), which suggests that PKIs, together with PIN , might mediate the phosphorylation of nNOS by PKA
Magee et al., Biol Reprod 2003 : In the central nervous system, nNOS is activated by the N-methyl-D-aspartate receptor ( NMDAR ) and, presumably, is inhibited by the protein inhibitor of NOS (PIN)
Dietz et al., Brain Res Mol Brain Res 2005 (Optic Nerve Injuries) : These results suggest that in our model, NOS activity is not regulated by altered PIN levels, which contributes to our understanding of apoptotic mechanisms in injured neurons
Yang et al., DNA Cell Biol 2008 : In this study we investigate the role of the protein inhibitor of NOS-1 (PIN) in the interferon-gamma (IFN-gamma) mediated posttranscriptional accumulation of nitric oxide synthase-1 (NOS-1) and the anti-vesicular stomatitis virus response in neuronal cells ... Overexpression of PIN results in lower constitutive NOS-1 expression and activity, and diminishes activation of NOS-1 by IFN-gamma
Rodríguez-Crespo et al., Arch Biochem Biophys 1998 : PIN reportedly inhibited nNOS selectively and did not interact with either the endothelial or inducible nitric oxide synthase isoforms ... However, PIN neither inhibits nNOS activity nor dissociates the nNOS dimer into monomeric species