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DUSP1 — TLR4
Text-mined interactions from Literome
Cho et al., Arch Biochem Biophys 2008
:
TLR4L treatment
induced MKP-1 through gene transcription
Wang et al., Mucosal Immunol 2010
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To gain insight into tolerance at the level of the proinflammatory mitogen activated protein kinase ( MAPK ) p38, we characterized
TLR mediated induction of the p38-specific phosphatase
MKP-1
Tsai et al., PloS one 2011
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These results strongly suggest that Der-p2 is capable of triggering B cell activation and
MKP-1 activated p38/MAPK dephosphorylation
regulated TLR4 induction, which subsequently enhances host immune, defense responses and development of effective allergic disease therapeutics in B cells