Gene interactions and pathways from curated databases and text-mining

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DUSP1 — HIF1A

Text-mined interactions from Literome

Liu et al., Biochem Biophys Res Commun 2003 (Anoxia...) : Inhibition of MKP-1 expression using siRNA technique could enhance HIF-1alpha phosphorylation, accompanied by an increase in transcriptionally active HIF-1 as well as a rise in the levels of HIF-1 induced erythropoietin expression
Liu et al., Exp Cell Res 2005 (Anoxia) : We have previously reported that mitogen activated protein kinase phosphatase DUSP1 ( MKP-1 ) was implicated in the negative regulation of HIF-1alpha subunit phosphorylation and HIF-1 activity
Liu et al., Zhonghua Yi Xue Za Zhi 2005 : Effects of MKP-1 or PD98059 on in vitro interaction between HIF-1alpha and p300 was determined by Pull-down assay coupled with Western bloting ... MKP-1 inhibits the in vitro interaction between HIF-1alpha and p300