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DEFB103B — TLR4

Text-mined interactions from Literome

Funderburg et al., Proc Natl Acad Sci U S A 2007 : Here, we show that human beta-defensin-3 (hBD-3) , an innate antimicrobial peptide, can induce expression of the costimulatory molecules CD80, CD86, and CD40, on monocytes and myeloid dendritic cells in a TLR dependent manner
Scharf et al., Respir Res 2010 : Inhibition of TLR2, TLR5 , and TLR9 expression led to a decreased hBD-3 expression
Semple et al., Eur J Immunol 2011 (Inflammation) : In addition, we show that hBD3 reduces NF-?B signaling in cells transfected with MyD88 or TRIF and that hBD3 inhibits the TLR4 response in both MyD88- and TRIF-deficient macrophages