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DDR1 — MAPK6

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: MAPK6 — DDR1 (direct interaction, two hybrid) Vinayagam et al., Science signaling 2011
• IRef Intact Interaction: MAPK6 — DDR1 (physical association, two hybrid) Vinayagam et al., Science signaling 2011

Text-mined interactions from Literome

Matsuyama et al., J Immunol 2003 (MAP Kinase Signaling System) : Activation of DDR1b on differentiated DDR1b overexpressing THP-1 cells or DDR1 on mature DCs induced the formation of TNFR associated factor 6 (TRAF6)/TGF-beta activated kinase 1 binding protein 1beta/p38alpha MAPK complex and p38alpha autophosphorylation ... Transfection of differentiated DDR1b overexpressing THP-1 cells with dominant negative TRAF6 completely abrogated DDR1b mediated p38 MAPK phosphorylation, indicating a critical role of TRAF6 in DDR1b mediated p38 MAPK activation
Matsuyama et al., Am J Respir Cell Mol Biol 2005 (Sarcoidosis, Pulmonary) : Activation of DDR1 induced monocyte chemoattractant protein-1 ( MCP-1 ) and matrix metalloproteinase-9 (MMP-9) production in a p38 mitogen activated protein kinase dependent manner from CD14 positive BALF cells of patients with deteriorated sarcoidosis
Ruiz et al., J Biol Chem 2011 (MAP Kinase Signaling System) : Furthermore, activation of DDR2, JAK2, and ERK1/2 MAPK signaling pathways was essential for collagen I-induced DDR1 and matrix metalloproteinase 10 expression