Gene interactions and pathways from curated databases and text-mining

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DAXX — MAP3K5

Pathways - manually collected, often from reviews:

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Charette et al., Mol Cell Biol 2000 : Here we show that phosphorylated dimers of HSP27 interact with Daxx , a mediator of Fas induced apoptosis, preventing the interaction of Daxx with both Ask1 and Fas and blocking Daxx mediated apoptosis
Junn et al., Proc Natl Acad Sci U S A 2005 (Parkinson Disease) : Interaction of DJ-1 with Daxx inhibits apoptosis signal regulating kinase 1 activity and cell death ... These findings suggest that the regulated sequestration of Daxx in the nucleus and keeping apoptosis signal regulating kinase 1 activation in check is a critical mechanism by which DJ-1 exerts its cytoprotective function
Chang et al., Science 1998 : Activation of apoptosis signal regulating kinase 1 ( ASK1 ) by the adapter protein Daxx