Gene interactions and pathways from curated databases and text-mining

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CYP7A1 — PRKAR2A

Text-mined interactions from Literome

Song et al., Hepatology 2006 : Reporter assays confirmed that cAMP and protein kinase A (PKA) inhibited human CYP7A1 gene transcription, in contrast to their stimulation of the PEPCK gene
Crestani et al., J Lipid Res 1995 (Second Messenger Systems) : Finally, cyclic AMP and protein kinase A (PKA) stimulated the expression of the CYP7/luciferase gene through multiple sequences in the distal and proximal regions, and both positive and negative response regions were mapped