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CYP2C19 — MAPK3
Text-mined interactions from Literome
Fleming et al., Pflugers Arch 2001
(MAP Kinase Signaling System) :
The
CYP 2C product 11,12-epoxyeicosatrienoic acid ( 11,12-EET ) also
activated tyrosine kinases,
Erk1/2 and p38 MAP kinase
Verma et al., Mol Pharmacol 2005
:
However, accumulation of activated extracellular signal regulated kinase ( ERK ) 1 and ERK2 were the only transducers measured in the study not affected by the 1 % replacement pulse of growth hormone and were elevated 2- to 3-fold above normal when the pulse was renaturalized to 10 % of physiological amplitude, suggesting the possible
involvement of
mitogen activated protein kinase in episodic growth hormone regulation of
CYP2C11