Gene interactions and pathways from curated databases and text-mining

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CYP2C19 — MAPK3

Text-mined interactions from Literome

Fleming et al., Pflugers Arch 2001 (MAP Kinase Signaling System) : The CYP 2C product 11,12-epoxyeicosatrienoic acid ( 11,12-EET ) also activated tyrosine kinases, Erk1/2 and p38 MAP kinase
Verma et al., Mol Pharmacol 2005 : However, accumulation of activated extracellular signal regulated kinase ( ERK ) 1 and ERK2 were the only transducers measured in the study not affected by the 1 % replacement pulse of growth hormone and were elevated 2- to 3-fold above normal when the pulse was renaturalized to 10 % of physiological amplitude, suggesting the possible involvement of mitogen activated protein kinase in episodic growth hormone regulation of CYP2C11