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CXCR1 — CXCR4

Pathways - manually collected, often from reviews:

• Reactome Reaction: CXCR1 → CXCR4 (reaction) Lerea et al., Neuron 1989, Van Dop et al., Nucleic Acids Res 1989, Itoh et al., J Biol Chem 1988, Takami et al., Brain Res Mol Brain Res 1994

Text-mined interactions from Literome

Corcione et al., J Natl Cancer Inst 2000 (Lymphoma, Follicular) : Such response was mediated by the SDF-1 receptor , CXCR4
Liu et al., Blood 2012 (Immunologic Deficiency Syndromes...) : Accordingly, like CXCR4 ( R334X ), the most common truncation mutation in WHIM syndrome, CXCR4 ( E343K ) mediated approximately 2-fold increased signaling in calcium flux and chemotaxis assays relative to wild-type CXCR4 ; however, CXCR4 ( E343K ) had a reduced effect on blocking normal receptor down-regulation from the cell surface
Ma et al., J Biol Chem 2013 (Atherosclerosis...) : Furthermore, CXCR7 activation increased macrophage phagocytic activity, which was suppressed by CXCR7 siRNA silencing or by inhibiting either the JNK or p38 pathways, but was not affected by blocking CXCR4