Gene interactions and pathways from curated databases and text-mining

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CHUK — CXCL12

Text-mined interactions from Literome

Yang et al., Clin Cancer Res 2006 (Melanoma) : Inhibition of constitutive IKK activity by BMS-345541 resulted in the reduction of NF-kappaB activity, CXCL1 chemokine secretion by cultured melanoma cells and melanoma cell survival in vitro and in vivo
Edwards et al., Mol Immunol 2007 : Focusing on CXCL8, both rhinovirus infection and dsRNA treatment required IkappaB kinase-beta for induction of CXCL8
Huang et al., J Cell Physiol 2009 (MAP Kinase Signaling System...) : Stimulation of cells with SDF-1alpha induced IkappaB kinase ( IKKalpha/beta ) phosphorylation, IkappaB phosphorylation, p65 Ser ( 536 ) phosphorylation, and kappaB-luciferase activity