Gene interactions and pathways from curated databases and text-mining

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CSRP1 — MAPK3

Text-mined interactions from Literome

Chen et al., Thromb Res 2008 : The effects of CRP on MAPK p38 phosphorylation was also studied by Bio-Plex luminex immunoassay
Kawahara et al., Cardiovasc Pathol 2008 (Inflammation) : CRP triggered the activation of p38MAPK and ERK1/2, but not Jun N-terminal kinase
Montecucco et al., Rheumatology (Oxford) 2009 : Treatment with L-mevalonate or farnesylpyrophosphate, but not geranylgeranyl-pyrophosphate reversed the statin induced effect on CRP mediated functions and ERK 1/2 phosphorylation, confirming that statins blocked CRP induced ERK 1/2 phosphorylation through the inhibition of 3-hydroxy-3-methylglutaryl coenzyme A ( HMG-CoA) reductase
Kikuchi et al., Exp Lung Res 2009 : Western blot analysis showed that CRP inhibited the p38 mitogen activated protein kinase ( MAPK ) activity in the presence of HFn