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CSK — MAPK3

Text-mined interactions from Literome

Daulhac et al., J Biol Chem 1999 : Expression of Csk , which inactivates Src-family kinases, totally inhibited gastrin induced Src-like activity detected in anti-Src and anti-Shc precipitates but diminished by 50 % Shc phosphorylation and ERK-1 activation
Zagozdzon et al., Cell Signal 2006 (MAP Kinase Signaling System) : In this work, we compared the effect of CHK versus Csk on MAPK signaling and elucidated the signaling pathway mediated by CHK leading to the activation of Erk1/2 ... Exogenous expression of wild-type CHK, but not Csk or a dead-kinase mutant of CHK, resulted in enhanced Erk1/2 phosphorylation in PC12 cells
Choudhury et al., Cell Signal 2006 : Inhibition of c-Src tyrosine kinase blocked PDGF stimulated MAPK activity and resulted in attenuation of c-fos gene transcription with concomitant prevention of Elk-1 transactivation
Beaulieu et al., Blood 2011 : Using Meg-01 cells and mouse megakaryocytes, we found that NF?B, ERK-MAPK , and PI3K/Akt pathways, known downstream pathways of TLRs, are activated by Pam3CSK4 , a TLR2-specific ligand