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CSK — IL12A

Text-mined interactions from Literome

Patel et al., J Immunol 2005 (Respiratory Hypersensitivity) : However, the anti-inflammatory effect of Pam3CSK4 was independent of IL-10 or TGF-beta, but was critically dependent on IL-12 , the production of which by dendritic cells was enhanced by Pam3CSK4 in vitro
Yang et al., Gastroenterology 2007 (Colitis) : In initial studies, we showed that splenocytes from NOD2 transgenic mice as compared with littermate controls exhibit decreased interleukin (IL)-12p70 responses to peptidoglycan ( PGN ), a TLR2 ligand that contains muramyl dipeptide, but not other TLR ligands ; in contrast, IL-12 responses to PAM ( 3 ) CSK ( 4 ), a TLR2 ligand that does not contain muramyl dipeptide, were normal
Lombardi et al., Clin Exp Allergy 2008 (Asthma...) : Among the three TLR2 ligands tested, the synthetic lipopeptide Pam3CSK4 is the most potent inducer of IL-12p35 and IL-10 gene expression in murine bone marrow derived DCs, as well as in purified oral myeloid DCs