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CSK — IGF1

Text-mined interactions from Literome

Arbet-Engels et al., J Biol Chem 1999 : The results suggest that c-Src and CSK are involved in IGF-IR and IR signaling and that the interaction of CSK with the IGF-IR may play a role in the decrease in c-Src activity following IGF-I stimulation
Sekimoto et al., Endocrinology 2003 : IGF-I stimulated CSK kinase activity 2-fold in differentiating 3T3-L1 cells ... These results suggest that the loss of IGF-I downstream mitogenic signaling in differentiating 3T3-L1 cells is due to a change in IGF-I activation of c-Src and CSK may mediate the inactivation of c-Src by IGF-I in 3T3-L1 adipogenesis
Duxbury et al., Oncogene 2004 (Adenocarcinoma...) : CEACAM6 overexpressing clones exhibited increased Akt and c-Src kinase activities, as well as higher levels of matrix metalloproteinase-2 (MMP-2) expression and activity in the presence of IGF-I