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CSF2 — EPO

Text-mined interactions from Literome

Hoenstein et al., Cell Immunol 2001 (Hypersensitivity, Immediate) : A significant increase of EPO release was induced by IL-2, IFN-gamma, and GM-CSF after 18 h in culture
Hermine et al., Blood 1992 (Leukemia, Megakaryoblastic, Acute) : On the other hand, Epo had no effect on number and affinity of GM-CSF receptors
Migliaccio et al., Blood 1990 (Agranulocytosis...) : As examples, maximal growth of granulocyte/macrophage ( GM ) colonies was induced by granulocyte/macrophage (GM)-CSF plus G-CSF in the patients, whereas a combination of GM-CSF, G-CSF and interleukin-3 (IL-3) was required in the normals, and erythropoietin alone induced fourfold more erythroid bursts from cyclic neutropenic patients than from normal donors ( 46 % versus 11 % of the maximal colony number, respectively )
Chen et al., Exp Hematol 2007 : In addition, our data confirmed that erythropoietin induced both erythroid and myeloid commitment, while granulocyte colony stimulating factor only supported the differentiation of the myeloid lineage
Teramura et al., Exp Hematol 1989 : Recombinant Epo did, however, produce a significant increase in the number and size of megakaryocyte colonies in the presence of rIL-3 or rGM-CSF
Van Zant et al., J Cell Biol 1983 : Erythropoietin causes down regulation of colony stimulating factor ( CSF-1 ) receptors on peritoneal exudate macrophages of the mouse
Minegishi et al., J Biol Chem 1994 : In contrast, the addition of GM-CSF to the M-TAT/EPO cell culture decreased the amount of hemoglobin, even in the presence of EPO, indicating that the EPO signal for erythroid differentiation is suppressed by GM-CSF
Hermine et al., Blood 1996 : The presence of GM-CSF significantly reduced the number of Epo-Rs expressed on parental UT-7 cells, but not on cells of clones 12, 10, and 6
Komatsu et al., Blood 1997 : Interestingly, GM-CSF inhibited the EPO- or TPO induced erythroid differentiation and the TPO induced megakaryocytic differentiation of UT-7/GM cells