Gene interactions and pathways from curated databases and text-mining

◀ Back to CASP7

CASP7 — CRYAB

Text-mined interactions from Literome

Ikeda et al., Biol Pharm Bull 2006 : The small heat shock protein alphaB-crystallin inhibits differentiation induced caspase 3 activation and myogenic differentiation ... Overexpression of alphaB-crystallin in C2C12 cells suppressed differentiation induced apoptosis and activation of caspase 3, and also decreased the expression of MyoD and myogenin during myogenic differentiation of C2C12 cells induced by the differentiation medium ... Our findings suggest that stress such as growth factor deprivation plays an important role in triggering apoptosis associated with myogenic differentiation and alphaB-crystallin suppressed the differentiation, apoptosis and caspase 3 activity
Sanbe et al., PloS one 2011 (Ion Channel Gating) : Nicorandil treatment also inhibited the increase in BAX, the decrease in BCL2, activation of caspase-3 and apoptotic cell death by mutant HSPB5