Gene interactions and pathways from curated databases and text-mining

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CRP — IL5

Text-mined interactions from Literome

Haider et al., Clin Exp Immunol 2006 (Endotoxemia) : LPS, interleukin (IL)-1 , IL-6 and tumour necrosis factor (TNF)-alpha increased and IL-10 reduced CRP expression in PBMC
Peroś-Golubicić et al., Acta Med Iugosl 1991 (Lung Diseases...) : It is well known that interleukin-1 , among other functions, stimulates the hepatic production of C-reactive protein
Mackiewicz et al., Biochem J 1988 : While both interleukin-1 and tumour necrosis factor regulate biosynthesis of a number of these acute phase proteins in rabbit primary hepatocyte cultures, neither of these monokines induced C-reactive protein synthesis
Zhang et al., Biochem J 1995 : The effect of interleukin-1 on C-reactive protein expression in Hep3B cells is exerted at the transcriptional level