Gene interactions and pathways from curated databases and text-mining

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CRH — IL5

Text-mined interactions from Literome

Cambronero et al., Regul Pept 1992 : Adrenalectomy does not change CRF secretion induced by interleukin-1 from rat perifused hypothalami
Krause et al., Horm Metab Res 2007 : alpha-Helical-CRF, a CRH antagonistic peptide, annulled the CRH effect on SZ95 sebocyte proliferation and interleukin secretion, while the non-peptidic CRH-R1 selective antagonist antalarmin inhibited the increased production of neutral lipids caused by CRH
Kageyama et al., J Endocrinol 2009 : Among them, interleukin (IL)-6 plays a role in the regulation of CRF
Sandi et al., Eur J Pharmacol 1995 : This study investigated the possibility that nitric oxide ( NO ) acts as a mediator of interleukin-1 induced CRF release ... The concurrent treatment with NG-nitro-L-arginine and indomethacin ( 14 microM ) -- an inhibitor of prostaglandin production -- reduced interleukin-1 induced CRF release to the same level as NG-nitro-L-arginine alone, suggesting that prostaglandins might interact with NO on this interleukin-1 effect
Kakucska et al., Endocrinology 1993 : Endotoxin induced corticotropin releasing hormone gene expression in the hypothalamic paraventricular nucleus is mediated centrally by interleukin-1
Dudley et al., Am J Obstet Gynecol 1999 (Obstetric Labor, Premature...) : The cytokine interleukin 1 stimulates production of corticotropin releasing hormone , and corticotropin releasing hormone in turn regulates cytokine production by immune effector cells