Gene interactions and pathways from curated databases and text-mining

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CRH — EPO

Text-mined interactions from Literome

Tringali et al., Endocrinology 2007 : Erythropoietin inhibits basal and stimulated corticotropin releasing hormone release from the rat hypothalamus via a nontranscriptional mechanism ... We observed that EPO ( 1-10 nm ) significantly reduced CRH release and, in parallel, increased intrahypothalamic CRH content
Zhang et al., Exp Hematol 1996 (Anemia...) : These results show that CRF can directly or indirectly can suppress the extrarenal production of EPO by the liver and that this effect may further aggravate the anemia of CRF