Gene interactions and pathways from curated databases and text-mining

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CNR2 — MAPK14

Text-mined interactions from Literome

Herrera et al., FEBS Lett 2005 (Leukemia) : p38 MAPK is involved in CB2 receptor induced apoptosis of human leukaemia cells ... Results show that stimulation of the CB2 receptor leads to p38 MAPK activation and that inhibition of this kinase attenuates CB2 receptor induced caspase activation and apoptosis ... These findings support a role for p38 MAPK in CB2 receptor induced apoptosis of human leukaemia cells
Signorello et al., J Cell Biochem 2011 : The 2-AG effect on p38MAPK was not impaired by apyrase, indomethacin or RGDS peptide but it was significantly reduced by SR141716, specific inhibitor of type-1 cannabinoid receptor and unaffected by the specific inhibitor of type-2 cannabinoid receptor SR144528