Gene interactions and pathways from curated databases and text-mining

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CLDN18 — MAPK6

Text-mined interactions from Literome

Murata et al., Exp Cell Res 2005 : In primary cultures of occludin-deficient mouse hepatocytes, claudin-2 expression and apoptosis were induced by down-regulation of the activation of MAPK and Akt ... In the hepatic cell lines derived from occludin-deficient mice, claudin-2 expression and serum-free induced apoptosis were also increased by down-regulation of the activation of MAPK and Akt
Yano et al., Am J Physiol Gastrointest Liver Physiol 2008 (Stomach Neoplasms) : Protein kinase C ( PKC ) and mitogen activated protein kinase ( MAPK ) inhibitors suppressed the upregulation of claudin-18a2