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CIT — NOS1

Text-mined interactions from Literome

Chapman et al., Pediatr Res 2012 : We investigated whether Arg or its precursor, citrulline (Cit), protects intestinal tight junctions ( TJs ) from hypoxia ( HX ) and determined whether inducible nitric oxide ( NO ) plays a role.Methods : Neonatal piglet jejunal IPEC-J2 cell monolayers were treated with Arg or Cit , reversible and irreversible NO synthetase (NOS) inhibitors , and were exposed to HX
Todoroki et al., Mol Med 1998 (Neuroblastoma) : L-Cit competitively inhibited NOS activity, as indicated by an apparent Ki value of 65 nM