Gene interactions and pathways from curated databases and text-mining

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CIITA — SIRT1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Wu et al., Nucleic Acids Res 2011 : Two different types of stress stimuli, hypobaric hypoxia and oxidized low-density lipoprotein ( oxLDL ), induce the acetylation of CIITA and suppress its activity by inhibiting the SIRT1 expression and activity
Li et al., Nucleic Acids Res 2012 : Further analysis reveals that IFN-? requires class II transactivator (CIITA) to repress SIRT1 transcription