Gene interactions and pathways from curated databases and text-mining

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CHGA — MAPK14

Text-mined interactions from Literome

Mahata et al., Neuroscience 1999 : Expression of dominant negative ( inhibitory ) mutants of Sos, Ha-Ras, Rafl, mitogen activated protein kinase , ribosomal protein S6 serine kinase II ( CREB kinase ) or CREB ( KCREB ) each inhibited the nerve growth factor induced increase in chromogranin A promoter activity
Tang et al., Mol Pharmacol 1998 (Adrenal Gland Neoplasms...) : Chemical inhibition of either MAPK or MAPK kinase blocked the response of a transfected chromogranin A promoter to nicotine or protein kinase C activation [ by phorbol-12-myristate-13-acetate ( PMA ) ], although nicotine evoked catecholamine secretion was unaffected ... Expression of the CREB antagonist KCREB blocked the response of the chromogranin A promoter to nicotine, cAMP, or MAPK pathway activation by either chemical stimulation or cotransfection of active cascade components