Gene interactions and pathways from curated databases and text-mining

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CHGA — IGF1

Text-mined interactions from Literome

Lee et al., Endocrinology 1999 : IGF-I and TGF-alpha did not increase intestinal chromogranin A (CGA) gene expression, a marker of endocrine cells, or the density of PYY containing cells in the colon, indicating that the elevations in intestinal gut peptide gene expression by IGF-I and TGF-alpha are not due simply to an increased number of enteroendocrine cells
Mergler et al., Neuroendocrinology 2005 (Neuroendocrine Tumors...) : It is not known, whether VOCCs play a role in the IGF-1 dependent regulation of CgA secretion in NET cells ... We therefore studied the effects of IGF-1 on individual VOCC subtypes and characterized their role in mediating IGF-1 dependent regulation of CgA secretion in NET cells ... IGF-1 potently induced CgA secretion
Mergler et al., Neuroendocrinology 2007 (Neuroendocrine Tumors...) : Our previous study demonstrated that Ca ( 2+ ) -permeable cation channels play a role in IGF-1 induced secretion of chromogranin A in human neuroendocrine tumor ( NET ) cell line BON [ Mergler et al. : Neuroendocrinology 2006 ; 82 : 87-102 ]
Pugazhenthi et al., J Biol Chem 1999 : IGF-I stimulated chromogranin A gene expression by Northern blot analysis 3.7-fold