Gene interactions and pathways from curated databases and text-mining

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CEBPD — PRKAR2A

Text-mined interactions from Literome

Billiard et al., J Biol Chem 2001 : We thus define a pathway for PKA mediated activation of C/EBPdelta through its regulated nuclear import
Billiard et al., J Biol Chem 2001 : Inhibition of active PKA with targeted nuclear expression of PKA inhibitor had no effect on the subcellular location of C/EBPdelta but prevented hormone induced IGF-I gene activation, while cytoplasmic PKA inhibitor additionally caused the removal of C/EBPdelta from the nucleus ... Cytoplasmic PKA mediates nuclear localization of C/EBPdelta under basal conditions, and nuclear PKA stimulates its transcriptional activity upon hormone treatment