Gene interactions and pathways from curated databases and text-mining

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CDX2 — WNT11

Text-mined interactions from Literome

Guo et al., J Biol Chem 2004 (Colonic Neoplasms) : Finally, we show that colon cancer cells effectively reduce Cdx2 mediated inhibition of Wnt/beta-catenin/TCF transcriptional activity when compared with other model systems
Guo et al., Carcinogenesis 2010 (Colonic Neoplasms) : Considering the pivotal role of beta-catenin/TCF activity in driving proliferation of normal intestinal epithelial and colon cancer cells, our findings suggest a novel mechanism for Cdx2 mediated regulation of Wnt/beta-catenin signaling and cell proliferation
Beschorner et al., Histol Histopathol 2009 (Choroid Plexus Neoplasms) : In the intestine, Wnt signaling represses the expression of the tumor suppressor gene CDX2 via SOX9, a transcription factor, which is also expressed in the choroid plexus
Crissey et al., Gastroenterology 2011 (Malabsorption Syndromes) : Cdx2 regulates intestinal cell-cell adhesion, proliferation, and the transcriptional activities of Wnt and ß-catenin in cell culture systems
Liu et al., Cancer Biol Ther 2012 (Lung Neoplasms...) : CDX2 may serve as a tumor suppressor in lung cancer and inhibits lung cancer cell proliferation by suppressing Wnt signaling