Gene interactions and pathways from curated databases and text-mining

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CDKN2D — STAT3

Text-mined interactions from Literome

O'Farrell et al., J Immunol 2000 : Stat3 dependent induction of p19INK4D by IL-10 contributes to inhibition of macrophage proliferation ... An inducibly active Stat3 ( coumermycin-dimerizable Stat3-Gyrase B ), which suppresses J774 cell proliferation, also induced p19INK4D expression ... These data suggest that Stat3 dependent induction of p19INK4D mediates inhibition of proliferation ... These data indicate that Stat3 dependent induction of p19INK4D and Stat3 independent induction of p21CIP1 are important components of the mechanism by which IL-10 blocks proliferation in macrophages
Demoulin et al., Cell Growth Differ 2001 (Lymphoma...) : Using mutated IL-9 receptors, we showed that inhibition of proliferation was correlated with STAT1 and STAT3 activation by IL-9 and induction of the cell cycle inhibitor p19/ink4d , a STAT3 target gene
Narimatsu et al., Biochem Biophys Res Commun 1997 (Leukemia, Myeloid) : Association of Stat3 dependent transcriptional activation of p19INK4D with IL-6 induced growth arrest