Tokarsky-Amiel et al., Cancer Res 2013
:
The endogenous Cdkn2a products p19(ARF) and p16(Ink4a) were activated by the transgenic p14(ARF) through p53, revealing a senescence promoting feed-forward loop
Tan et al., Hum Mutat 2013
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Inhibition of chimeric p14ARF-FAM230A expression increased p14ARF and TBX1 expression and improved DNA repair
Kamijo et al., Cell 1997
(Leukemia, Erythroblastic, Acute...) :
The INK4a tumor suppressor locus encodes p16INK4a , an inhibitor of cyclin D-dependent kinases, and p19ARF , an alternative reading frame protein that also blocks cell proliferation